As I write this update, I’m feeling cautiously optimistic—something I haven’t said in a long time. Week two of my journey with Exenatide has brought some unexpected changes, and while I don’t want to get ahead of myself, I feel it’s worth sharing what I’ve experienced so far.

A Shift in the Tide
Week two started with some hesitation. I’d been bracing for the ups and downs that come with any experimental treatment, but I noticed something surprising: more good days than bad. Side Effects that dominated my day-to-day life, in week one, seemed to ease their grip just a little. I still have MSA, and every step remains a challenge, but for the first time in a while, I’m finding moments of relief.

Nutrition: A Vital Ally
One thing I’ve learned in this process is that nutrition plays a huge role in how my body responds to treatment. The researchers at MyTrial encouraged me to refine my diet, and I’m realizing how much of a difference it makes.
Here are some of the key guidelines I’m following:
• Avoid foods that are difficult to digest. My body doesn’t need extra challenges right now.
• Cut out red meat and gluten. These were hard habits to break, but they’ve made me feel less sluggish.
• Say no to sugar. It’s a killer—not just for overall health, but especially for someone like me managing the Symptoms of MSA.
It’s not easy. Cravings don’t disappear overnight, but knowing these choices might help me feel better keeps me motivated.

The Nitty-Gritty Details
Let’s talk about a topic no one likes to discuss: constipation. If you’ve been on this journey with MSA, you know how stubborn this issue can be. The Exenatide injections seem to make it even trickier, so I’ve made it a point to stay on top of it. Whether it’s through medications, over-the-counter remedies, or natural options, I’ve learned not to wait until it becomes a bigger problem.
Another adjustment I’ve made is where I take my Exenatide injections. Initially, I was injecting into my stomach, which left me feeling queasy. Switching to my leg has been a game-changer for managing nausea. It’s a small tweak, but it’s made a noticeable difference.

A Sparkle in My Eyes
Perhaps the most touching moment this week came from my wife. On day 14, as we were sitting together, she looked at me and said, “I’m so glad you’re feeling better. I can see a sparkle in your eyes that hasn’t been there for a long time.” 🙏❤️
Her words caught me off guard. I hadn’t realized how much MSA had dulled my spirit until I heard that. While I’m careful not to read too much into it, her observation gave me a glimmer of hope—a reminder that this journey isn’t just about physical symptoms but about reclaiming moments of joy and connection.

Cautious Optimism
I want to be clear: this isn’t a miracle cure, and I’m not claiming any breakthroughs. MSA is unpredictable, and setbacks are always possible. But for now, I’m taking these small victories one day at a time, with gratitude for every good moment.
To my fellow MSA warriors: hang in there. If you’re considering experimental treatments, know that it’s a journey of trial and error, hope and perseverance. Trust the process, lean on your support system, and never stop believing in the possibility of better days ahead.

What’s Next?
I’ll continue documenting my experience with Exenatide and share another update next week. My hope is that by sharing this journey, I can help others navigating MSA find hope, inspiration, and practical tips for their own path.
Until then, stay strong and stay hopeful.
~Coach~

FuckMSA 🙏❤️